NFkB p65 Mouse Monoclonal Antibody
Catalog NO.：BE3169
Applications ：WB IP IF IHC
Reactivity ：H,M,R
| 货号 | 规格 | 品牌 | 库存 | 价格 | 数量 | 操作 |
|---|---|---|---|---|---|---|
| BE3169-100 | 100μl/支 | EASYBIO |
|
|||
| BE3169-10 | 10μl/支 | EASYBIO |
|
|||
| BE3169-50 | 50μl/支 | EASYBIO |
|
NFkB p65 is ubiquitinated leading to its proteosomal degradation, which is required for termination of the NFkB response. Phosphorylation of NFkB p65 on S536 stimulates acetylation of K310 by CBP, enhancing transcriptional activity. NFkB p65 is also acetylated at K122, enhancing DNA binding and impairing the interaction with NFKBIA. The protein is deacetylated by HDAC3. Invasion of a host by a pathogen is frequently associated with the activation of NF-kB, which coordinates various aspects of immune function required for resistance to infection.
| Product Name: | NFkB p65 Mouse Monoclonal Antibody |
|---|---|
| Isotype: | IgG1 |
| Storage Buffer : | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol |
| Storage instructions: | -20°C. Do not aliquot the antibody |
| Recommended dilutions: | WB:1:500-2,000 IP:1:200 1:100-200 IF:1:200-500 |
| Optimal dilutions should be determined by the end user. | |
| Specificity： | NFκB p65 Mouse monoclonal antibody detects endogenous p65 proteins. |
| Alternative Names： | NF kappa B p65, NFKB3, p65, p65 NF kB, RELA, TF65, Transcription Factor p65 |
| Form: | Liquid |
| Reactivity: | H,M,R |
