PARP Mouse Monoclonal Antibody
Catalog NO.：BE3172
Applications ：WB IHC
Reactivity ：H
| 货号 | 规格 | 品牌 | 库存 | 价格 | 数量 | 操作 |
|---|---|---|---|---|---|---|
| BE3172-100 | 100μl/支 | EASYBIO |
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| BE3172-10 | 10μl/支 | EASYBIO |
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| BE3172-50 | 50μl/支 | EASYBIO |
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Poly [ADP-ribose] polymerase 1 (PARP-1) also known as NAD+ ADP-ribosyltransferase 1 or poly[ADP-ribose] synthase 1 is an enzyme that in humans is encoded by the PARP1 gene. PARP1 has a role in repair of single-stranded DNA (ssDNA) breaks. Knocking down intracellular PARP1 levels with siRNA or inhibiting PARP1 activity with small molecules reduces repair of ssDNA breaks. In the absence of PARP1, when these breaks are encountered during DNA replication, the replication fork stalls, and double-strand DNA (dsDNA) breaks accumulate.
| Product Name: | PARP Mouse Monoclonal Antibody |
|---|---|
| Isotype: | IgG1 |
| Storage Buffer : | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol |
| Storage instructions: | -20°C. Do not aliquot the antibody |
| Recommended dilutions: | WB:1:1,000-3,000 IHC:200-500 |
| Optimal dilutions should be determined by the end user. | |
| Specificity： | Antibody can detects endogenous PARP protein. |
| Alternative Names： | PARP-1, Poly(ADP ribose) polymerase 1, sPARP1,ADPRT1, ADP ribosyltransferase NAD(+) |
| Form: | Liquid |
| Reactivity: | H |
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